Skip Navigation

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (16)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Abogadie, F. C.
Right arrow Articles by Farbman, A. I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Abogadie, F. C.
Right arrow Articles by Farbman, A. I.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Chemical Senses 20: 199-206,
© 1995

research-article

G-protein Subunits Expressed in Catfish Olfactory Receptor Neurons

Fe C. Abogadie, Richard C. Bruch and Albert I. Farbman

Department of Neurobiology and Physiology, Northwestern University Evanston, IL 60208, USA

Correspondence to be sent to: Richard C Bruch, Department of Zoology and Physiology, Louisiana State University, Baton Rouge, LA 70803, USA

Olfactory signal transduction in a number of species has been shown to be mediated by heterotrimeric GTP-binding proteins (G-proteins). The expression of different G-proteins in channel catfish (Ictalurus punctatus) olfactory epithelium was investigated using antibodies to both the {alpha} and ß subunits of G-proteins. Based on Western blotting and immunohistochemical data, the following G-protein subunits were identified in the olfactory epithelium: Gs/Golf, Gi1, Gi2, Gq and Gß. Immunohistochemical results indicated that all of these G-proteins, encompassing three G-protein subfamilies, were expressed in the dendrites and cilia of olfactory receptor neurons. These findings suggest that different G-protein subunits may mediate multiple signal transduction pathways in the catfish olfactory system, i.e. Golf/Gs, may mediate odorant activation of adenylyl cyclase while Gi and Gß may mediate odorant activation of phospholipase C.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J. Neurosci.Home page
A. Hansen, S. H. Rolen, K. Anderson, Y. Morita, J. Caprio, and T. E. Finger
Correlation between Olfactory Receptor Cell Type and Function in the Channel Catfish
J. Neurosci., October 15, 2003; 23(28): 9328 - 9339.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.